Publications by authors named "S Brophy"

Purpose: Health and Attainment of Pupils in a Primary Education National (HAPPEN) is a primary school national cohort which brings together education, health and well-being research in line with the Curriculum for Wales framework. Health, education and social care data are linked and held in the Secure Anonymised Information Linkage (SAIL) Databank. In addition, school-aged children complete the HAPPEN Survey to inform the design and implementation of the Health and Well-being curriculum.

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Article Synopsis
  • The study explores factors influencing the start and stop of anti-IL-6 biologic DMARDs versus other bDMARDs in rheumatoid arthritis patients.
  • It analyzed data from a Welsh health database, focusing on treatment initiation and outcomes like infections and hospitalizations.
  • Findings show that anti-IL-6 bDMARDs were often chosen by patients with prior infections or kidney issues, and these patients had a lower treatment discontinuation rate compared to those on non-anti-IL-6 therapies.
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Objective: To examine if the weight of a child determines adverse events following oral antibiotics prescription.

Design: Population respective cohort using linked general practice (GP), hospital data and linkage with the Welsh Demographic Service for demographic information. Data linkage was performed using Wales health data, extracted from the SAIL (Secure Anonymised Information Linkage) databank.

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Background: Research consistently finds poorer health and educational outcomes for children who have experienced out-of-home care relative to the general population. Few studies have explored differences between those in care and those in receipt of intervention from social services but not in care. Children receiving social services interventions often experience Adverse Childhood Experiences (ACEs), and deprivation, which are known to negatively impact outcomes.

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