Publications by authors named "S Broggi"
Article Synopsis
- - A 20-year-old man with drug-resistant epilepsy developed multiple intracerebral hemorrhages after receiving stereo-EEG electrodes and experiencing a lumbar spinal tap, with a history of heavy use of nicotine pouches.
- - Genetic testing revealed a mutation in the COL4A2 gene, which is linked to collagen production and has previously been associated with hemorrhage risks, raising concerns about its role in the patient's complication.
- - The study suggests that the combination of the COL4A2 mutation and high nicotine use could significantly increase the likelihood of bleeding during neurosurgical procedures, calling for more research into this connection.
Purpose: The proximity or overlap of planning target volume (PTV) and organs-at-risk (OARs) poses a major challenge in stereotactic body radiation therapy (SBRT) of pancreatic cancer (PACA). This international treatment planning benchmark study investigates whether simultaneous integrated boost (SIB) and simultaneous integrated protection (SIP) concepts in PACA SBRT can lead to improved and harmonized plan quality.
Methods And Materials: A multiparametric specification of desired target doses (gross target volume [GTV], GTV, PTV, and PTV) with 2 prescription doses of GTV = 5 × 9.
Article Synopsis
- - Oropharyngeal cancer (OphC) during pregnancy is rare but may become more common, and delays in treatment can negatively impact survival; current data on radiation therapy's effects on pregnant patients and their children are limited.
- - A case study describes a 39-year-old pregnant woman with advanced OphC who received surgery and radiation therapy, using techniques to minimize fetal radiation exposure, with an estimated dose of about 50 mSv.
- - The patient remained cancer-free after 10 years, and her daughter, born at nearly 34 weeks, is healthy and performing well in school, suggesting that optimizing radiation treatment during pregnancy can protect both mother and child.
Background: Despite the increased use of mechanical thrombectomy (MT) in recent years, there remains a lack of research on in-hospital mortality rates following the procedure, the primary factors influencing these rates, and the potential for predicting them. This study aimed to utilize interpretable machine learning (ML) to help clarify these uncertainties.
Methods: This retrospective study involved patients with anterior circulation large vessel occlusion (LVO)-related ischemic stroke who underwent MT.
Purpose: The purpose of this study is to investigate the dosimetric characteristics of a collimator for minibeam radiotherapy (MBRT) with film dosimetry and Monte Carlo (MC) simulations. The outcome of MBRT with respect to conventional RT using a glioma preclinical model was also evaluated.
Methods: A multi-slit collimator was designed to be used with commercial small animal irradiator.