Adaptation of the herpetic virus on human diploid and monkey kidney cells.

Viral suspensions of herpetic virus were inoculated on different cell cultures: human diploid cells (HDC) and monkey kidney cells--primary culture and cell line--for adapting the virus on these cells and obtaining several high constant titers. The human diploid cells and the monkey kidney cell line have proved to be the most suitable cells for the virus growth; thus an optimum development of the virus with a high constant titer was obtained starting with the 4th passage (10(5.7)-10(6)CPD/50/ml).

Treatment and prophylaxis of recurrent genital herpes using vaccinia immunostimulant (Antiherpin).

192 patients, 72 women and 120 men, aged 18-75, presenting genital herpes, were followed. Among these, 122 formed the test batch, exclusively with Antiherpin, and 70 represented the control batch, treated with other therapeutic preparations. Antiherpin was administered by percutaneous route, by scarification.

[Hemorrhagic syndrome in newborn infants during a hospital infection with Pseudomonas aeruginosa].

In a department for neonates 21 of the 34 children contracted infections with various clinical manifestations within a relatively short interval (approximately two weeks). Three of the children died and pathoanatomic examination revealed aspects characteristic of vascularitis and diffuse hemorrhage in most organs accompanied by infiltration and oedema. From the lethal cases, part of the sick and healthy children and personnel the same bacterium was isolated--Pseudomonas aeruginosa, suggesting an in-hospital epidemic.