Publications by authors named "S Bradberry"
Introduction: Alcohol withdrawal is typically managed using benzodiazepines. However, modulation of both γ-aminobutyric acid-A and N-methyl-d-aspartate-receptors through ethanol provision may provide an alternative management strategy. This systematic review critically analyses the evidence surrounding the use of oral or intravenous ethanol for the management of alcohol withdrawal syndrome.
View Article and Find Full Text PDFThere is an increasing awareness of the link between chronic alcohol consumption and the development of cognitive, behavioural and functional deficits. Currently, preventative strategies are limited and require engagement in dedicated long-term rehabilitation and sobriety services, the availability of which is low. The acute alcohol withdrawal syndrome is an episode of neurochemical imbalance leading to autonomic dysregulation, increased seizure risk and cognitive disorientation.
View Article and Find Full Text PDFObjective: To evaluate a decade of reported paediatric opioid poisoning cases in the UK.
Methods: The National Poisons Information Service (NPIS) telephone enquiries database (UK Poisons Information Database) was searched for calls regarding opioid poisoning in children under 18 years from 2012 to 2021. The NPIS online clinical guidance database TOXBASE was searched for accesses relating to opioids for both adults and children.
Article Synopsis
- A study was conducted to evaluate the use of oral ethanol as an alternative to benzodiazepines for managing alcohol withdrawal syndrome in patients within a UK health service setting.
- The research included a retrospective review of patients treated with either ethanol or benzodiazepines, focusing on those at high risk for severe withdrawal symptoms such as delirium tremens.
- Results indicated that patients managed with ethanol had a significantly lower likelihood of hospital admission, suggesting that oral ethanol could be a viable treatment option during alcohol withdrawal management.