Publications by authors named "S Bourigua"

Article Synopsis
  • A new biosensor for detecting trimethylamine (TMA) has been developed, which indicates fish freshness and is based on a conducting polypyrrole with ferrocenyl substitution, featuring the immobilized enzyme flavin-containing monooxygenase 3 (FMO3).
  • The biosensor operates by measuring the current response of ferrocenyl groups as TMA is oxidized to trimethylamine N-oxide, and it employs both amperometric and impedimetric techniques for detection across a range of TMA concentrations (0.4 to 80 μg/mL).
  • The results show high sensitivity, stability over 16 days, and effective selectivity in real fish samples, confirming its potential for monitoring fish quality during storage.
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Measurement of D-dimer has subsequently become an essential element in the diagnostics of deep vein thrombosis and pulmonary embolism; in this context microelectrodes with an area of 9×10(-4) cm(2) were used to develop impedimetric immunosensor for detecting deep venous thrombosis biomarker (D-dimer). The biosensor is based on functionalized carbon nanotubes (SWCNT-COOH) where the antibody (anti-D-dimer) was immobilized by covalent binding. The electrical properties and the morphology of the biolayer were characterized by electrochemical impedance spectroscopy (EIS), cyclic voltammetry and atomic force spectroscopy (AFM).

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