Laser Megajoule performance status.

The Laser Megajoule (LMJ) is among the most energetic inertial confinement fusion laser facilities in the world, together with the National Ignition Facility (NIF) in the USA. The construction of the facility began back in 2003, and the first photons were emitted by the laser bundle #28 in 2014. Today, 11 laser bundles consisting of 88 large aperture 0.

A negative feedback loop is critical for recovery of RpoS after stress in Escherichia coli.

RpoS is an alternative sigma factor needed for the induction of the general stress response in many gammaproteobacteria. Tight regulation of RpoS levels and activity is required for bacterial growth and survival under stress. In Escherichia coli, various stresses lead to higher levels of RpoS due to increased translation and decreased degradation.

RpoS and the bacterial general stress response.

SUMMARYThe general stress response (GSR) is a widespread strategy developed by bacteria to adapt and respond to their changing environments. The GSR is induced by one or multiple simultaneous stresses, as well as during entry into stationary phase and leads to a global response that protects cells against multiple stresses. The alternative sigma factor RpoS is the central GSR regulator in and conserved in most γ-proteobacteria.

Defining Two Chemosensory Arrays in .

has 2 functional chemosensory systems named Che1 and Che3, and 27 chemoreceptors. Che3 is dedicated to chemotaxis while Che1 could be involved in RpoS post-translational regulation. In this study, we have shown that two chemoreceptors Aer2so and McpAso, genetically related to the Che1 system, form distinct core-signaling units and signal to Che1 and Che3, respectively.