Publications by authors named "S Bombardieri"
Objective: To optimise the organisation of care and encourage the adoption of good clinical practices, the RarERN Path methodology was designed within ERN ReCONNET. The aim of our work was to report the application of RarERN Path on systemic sclerosis within the ERN ReCONNET centres, providing a feasible and flexible organisational reference model for optimising the systemic sclerosis care pathway in different countries.
Methods: RarERN Path is a six-phase methodology which enables the creation of a reference organisational model co-designed on the basis of the expertise of different stakeholders.
Introduction: Evidence from randomised controlled trials on anti-tumour necrosis factor (TNF) agents in patients with Behçet's syndrome (BS) is low.
Method: We conducted a phase 3, multicentre, prospective, randomised, active-controlled, parallel-group study to evaluate the efficacy and safety of either infliximab (IFX) or adalimumab (ADA) in patients with BS. Adults patients with BS presenting with active mucocutaneous manifestations, occurring while on therapy with either azathioprine or cyclosporine for at least 3 months prior to study entry, were eligible.
Background: Vaccination is one of the most important measures to contain the COVID-19 pandemic, especially for frail patients. VACCINATE is a multicentre prospective observational study promoted by the European Reference Network on Rare and Complex Connective Tissue and Musculoskeletal Diseases (ERN ReCONNET) aimed at assessing the long-term outcomes of COVID-19 vaccination in patients with rare and complex connective tissue diseases (rcCTDs) in terms of efficacy and safety.
Methods: Adult rcCTDs patients were eligible for recruitment.
Article Synopsis
- - The study investigates how environmental factors, specifically climate-related natural hazards, may affect the diagnosis and symptoms of Sjögren's syndrome across different countries, examining aspects like epidemiological profiles and sicca symptoms.
- - Researchers analyzed data from 16,042 patients in 23 countries, determining that those in countries severely impacted by climate hazards (like extreme precipitation and flooding) were often diagnosed with Sjögren's syndrome earlier and exhibited varying symptom frequencies.
- - Findings revealed statistically significant patterns, indicating lower occurrences of dry eyes and mouth in patients from countries facing specific climate threats, while showing that increased climate-related risks correlated with higher disease activity scores (ESSDAI).