Efficacy and Tolerance of Vascular Electrical Stimulation Therapy in the Management of Vaso-Occlusive Crises in Patients with Sickle Cell Disease: A Phase II Single-Centre Randomized Study in Ivory Coast.

Background: Vaso-occlusive crisis (VOC) is the primary cause of hospitalization in patients with sickle cell disease. Treatment mainly consists of intravenous morphine or nonsteroidal anti-inflammatory drugs (NSAIDs), which have many dose-related side effects. The question arises as to whether vascular electrical stimulation therapy (VEST) could be effective or not on VOCs.

[Prevalence of Chronic Complications of Sickle Cell Disease at the Bobo-Dioulasso Teaching Hospital, Burkina Faso].

This is a descriptive cross-sectional unicentric study, with a prospective collection of data on the frequency of chronic complications of sickle cell disease in patients monitored at Souro Sanou University Hospital in Bobo-Dioulasso in the department of medicine conducted from April 1, 2017 to July 31, 2018. Patients with confirmed adult sickle cell disease, at least 16 years of age, who had given oral consent, was seen at least twice in the inter-critical period during the study, and who had performed a biological and / or radiological screening for chronic complications. Out of 144 sickle cell patients seen, 79 met our inclusion criteria.