African Swine Fever in Saxony-Disease Dynamics.

African swine fever (ASF) emerged in Germany in 2020. A few weeks after the initial occurrence, infected wild boar were detected in Saxony. In this study, data from wild boar surveillance in Saxony were analyzed.

African swine fever: advances and challenges.

African swine fever (ASF) has become a major focus of research after spreading to four continents besides Africa. In its natural African ecosystem, the causative ASF virus (ASFV) is maintained by indigenous Suidae as natural reservoirs and hard tick vectors. However, in Sus scrofa domesticated breeds and wild boar, ASFV causes devastating disease, with mortalities reaching over 90%.

Predicting long-term pain by combining brain imaging, genetics and health questionnaire data with Swedish national registries using a prospective superstruct design.

Background: Long-term pain is a common health problem that results in disability for patients of all ages, leading to an enormous economic burden. Over 20% of the population suffer from long-term pain. Unfortunately, there are no clinical tests that predicts who will develop long-term pain.

A Standardized Pipeline for Assembly and Annotation of African Swine Fever Virus Genome.

Obtaining a complete good-quality sequence and annotation for the long double-stranded DNA genome of the African swine fever virus (ASFV) from next-generation sequencing (NGS) technology has proven difficult, despite the increasing availability of reference genome sequences and the increasing affordability of NGS. A gap analysis conducted by the global African swine fever research alliance (GARA) partners identified that a standardized, automatic pipeline for NGS analysis was urgently needed, particularly for new outbreak strains. Whilst there are several diagnostic and research labs worldwide that collect isolates of the ASFV from outbreaks, many do not have the capability to analyze, annotate, and format NGS data from outbreaks for submission to NCBI, and some publicly available ASFV genomes have missing or incorrect annotations.