Publications by authors named "S Blanco Mejia"

Aggrecan (ACAN) is a large, secreted chondroitin sulfate proteoglycan that includes three globular regions named G1, G2, G3, and is decorated with multiple glycosaminoglycan attachments between its G2 and G3 domains. The N-terminal G1 region interacts with the glycosaminoglycan hyaluronan (HA), which is an essential component of the vertebrate extracellular matrix. In the central nervous system, ACAN is found in perineuronal nets (PNNs), honeycomb-like structures that are enriched on parvalbumin-positive neurons in specific neural circuits.

View Article and Find Full Text PDF

Recent decades have witnessed a worldwide decline in international poverty. Conventional explanations of this empirical problem emphasize variables tied to domestic and global economic processes. This analysis provides an alternative explanation, where I develop a neo-institutional theory of international poverty.

View Article and Find Full Text PDF
Article Synopsis
  • * Traditional imaging techniques can help rule out conditions like urinary obstruction but still fall short in providing a clear diagnosis for the underlying causes of AKI.
  • * There is growing interest in developing new urine and blood biomarkers that could lead to better diagnostic tools, particularly for conditions like acute interstitial nephritis and damage from chemotherapy, which might significantly enhance patient care and outcomes.
View Article and Find Full Text PDF

Background: Many clinical practice guidelines recommend dietary pulses for the prevention and management of cardiovascular disease and diabetes. The impact of extracted pulse proteins remains unclear. We therefore conducted a systematic review and meta-analysis of randomized controlled trials of the effect of extracted pulse proteins on therapeutic lipid targets.

View Article and Find Full Text PDF
Article Synopsis
  • There is a growing push for increased plant food consumption, particularly soy foods, which have potential health benefits for women, despite ongoing controversies regarding their effects.
  • A systematic review and meta-analysis of 40 randomized trials involving over 3,000 postmenopausal women were conducted to assess the impacts of soy isoflavones on various estrogen-related measures.
  • The results showed no significant effects of soy isoflavones on endometrial thickness, vaginal maturation, follicle-stimulating hormone, or estradiol levels, indicating that they may function as selective estrogen receptor modulators rather than acting like estrogen itself.
View Article and Find Full Text PDF