Untangling the Efficient Boron-Initialized Hydroxyl-Terminated Polybutadiene Combustion for High Energetic Solid Propulsion Systems.

Highly energetic boron (B) particles embedded in hydroxyl-terminated polybutadiene (HTPB) thermosetting polymers represent stable solid-state fuel. Laser-heating of levitated B/HTPB and pure HTPB particles in a controlled atmosphere revealed spontaneous ignition of B/HTPB in air, allowing for examination of the exclusive roles of boron. These ignition events are probed via simultaneous spectroscopic diagnostics: Raman and infrared spectroscopy, temporally resolved high-speed optical and infrared cameras, and ultraviolet-visible (UV-vis) spectroscopy.

Metal complex-based probes for the detection of chloride ions.

Chloride ions play vital roles in a variety of biological and environmental processes, making their accurate and efficient detection critical for both research and practical applications. In this perspective, we explore the recent advancements in the development of metal complex-based probes for chloride ion detection, with a focus on complexes involving transition and lanthanide metals. These probes offer remarkable selectivity and sensitivity, achieved through diverse mechanisms such as metal coordination, hydrogen bonding, electrostatic interactions, and halogen or chalcogen bonding.

Integrative metabolomic-proteomic analysis uncovers a new therapeutic approach in targeting rheumatoid arthritis.

Objective: Rheumatoid arthritis (RA) is a chronic inflammatory condition that, despite available approaches to manage the disease, lacks an efficient treatment and timely diagnosis. Using the most advanced omics technique, metabolomics and proteomics approach, we explored varied metabolites and proteins to identify unique metabolite-protein signatures involved in the disease pathogenesis of RA.

Methods: Untargeted metabolomics (n = 20) and proteomics (n = 60) of RA patients' plasma were carried out by HPLC/LC-MS/MS and SWATH, respectively and analyzed by Metaboanalyst.

Definitions, etiopathogenesis and epidemiology of ALF.

Acute liver failure (ALF) is a rare but preventable cause of acute hepatic dysfunction which is associated with significant mortality, unless treated appropriately. There are significant regional variations in the etiologies of ALF globally and this determines the outcomes of the disease as well as the long-term survival in patients receiving liver transplantation for management. Improvements in understanding of disease pathophysiology and critical care medicine have led to better outcomes over the last few decades.

Beyond predation: Fish-coral interactions can tip the scales of coral disease.

Coral reefs are critical ecosystems, fostering biodiversity and sustaining the livelihoods of millions globally. Nonetheless, they confront escalating threats, with infectious diseases emerging as primary catalysts for extensive damage, surpassing the impacts of other human-induced stressors. Disease transmission via biotic factors, particularly during fish predation, is a crucial yet often overlooked pathway.