Publications by authors named "S Binici"

Article Synopsis
  • The study investigates the role of specific SNPs in the CDH1 gene and their association with gastric cancer risk, focusing on three SNPs: rs16260, rs13689, and rs9929218.
  • Among the SNPs, only rs13689 showed a significant association with gastric cancer, as patients had a much higher frequency of the T allele compared to healthy controls, indicating a fourfold increased risk.
  • The findings suggest that the T allele of rs13689 may significantly contribute to susceptibility to gastric cancer, while the other two SNPs may have implications for smokers.
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Breast cancer treatment encompasses various therapeutic modalities, including surgery, radiotherapy, and chemotherapy. Breast-conserving surgery has been an integral part of breast cancer management. However, radiotherapy, an important component of breast cancer management, can lead to complications, particularly fibrosis, affecting reconstructive surgery outcomes.

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Purpose: Breast cancer is the most common malignancy accounting for 11.7% of all cancer cases, with a rising incidence rate. Various diagnostic methods, including 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT), play a crucial role in breast cancer diagnosis and staging.

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Objective: The prognosis of breast cancer (BC) is determined directly based on the stage of disease at the time of diagnosis. Proliferative breast lesions (PBLs) are an important risk factor for BC development. The risk of developing BC varies according to the presence of extent of proliferation in the breast lesions.

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