Publications by authors named "S Bilia"
Adult-onset Still's disease: analysis of a monocentric cohort of patients.
Scand J Rheumatol
July 2024
Objective: Adult-onset Still's disease (AOSD) is a multigenic autoinflammatory disease with a severe systemic involvement. Because of the rarity of the disease, most published cohorts are multicentric. The aim of this report is to describe a monocentric cohort of AOSD patients, reporting clinical features and response to therapy in a long follow-up.
View Article and Find Full Text PDFUrticarial vasculitis (UV) is a small-vessel leukocytoclastic vasculitis characterized by different clinical manifestations ranging from long-lasting urticarial lesions to severe and potentially life-threatening multi-organ involvement. Omalizumab (OMA), anti-IgE recombinant humanized IgG1 monoclonal antibody, has been successfully used to treat few cases of severe and/or refractory UV. In this study we report our experience on 6 patients with refractory normocomplementemic UV successfully treated with anti-IgE therapy (OMA), suggesting that this biological therapy may be a safe and effective therapeutic option in UV.
View Article and Find Full Text PDFArticle Synopsis
- Autoimmune systemic diseases (ASD) increase the likelihood of contracting COVID-19, with a study of nearly 4,000 Italian ASD patients revealing a higher infection rate compared to the general population.
- While ASD patients had more cases of COVID-19, their death rate was similar to that of the overall Italian population, though systemic sclerosis patients faced a higher risk of mortality.
- Key factors influencing the severity of COVID-19 in ASD patients included older age, male gender, and certain medical treatments, with those on specific medications showing a significantly lower infection prevalence.