Brainstem encephalitis (BE), a rare and potentially fatal condition, can lead to significant neurological impairments, including cerebellar ataxia. This case report describes a 23-year-old female who presented with weakness in both upper and lower limbs, seizures, and an ataxic gait pattern following a history of sepsis-related brainstem encephalitis. Magnetic resonance imaging (MRI) revealed gross cerebellar atrophy.
View Article and Find Full Text PDFThe most prevalent malignant tumor in the oral cavity is squamous cell carcinoma (SCC). Social interactions are impeded, including eating, conversing, and practicing basic oral hygiene. A 43-year-old man who had previously suffered pus discharge in the right side of the buccal mucosa complained of dull aching in the lower right back of his jaw.
View Article and Find Full Text PDFThe physiotherapy rehabilitation program aims to build up functional activity, coordination, and balance ambulation for proper independence in the activities of daily living. An uncommon but complicated neurological condition called autoimmune encephalopathy is caused by the body's immune system mistakenly attacking healthy brain tissue. This condition often leads to a wide range of neurological and cognitive symptoms, making its diagnosis and treatment challenging.
View Article and Find Full Text PDFUnlabelled: SSB_W2, isolated from Mahabaleshwar in the Western Ghats of Maharashtra, India, was employed to enhance laccase production in solid-state fermentation (SSF). The spectral analysis indicated that the laccase produced by is a typical yellow laccase, exhibiting no absorption at 600 nm. Notably, this yellow laccase demonstrated exceptional catalytic activity, as confirmed by electrochemical analysis.
View Article and Find Full Text PDFProtein A chromatography is an enabling technology in current manufacturing processes of monoclonal antibodies (mAbs) and mAb derivatives, largely due to its ability to reduce the levels of process-related impurities by several orders of magnitude. Despite its widespread application, the use of mathematical modeling capable of accurately predicting the full protein A chromatographic process, including loading, post-loading wash and elution stages, has been limited. This work describes a mechanistic modeling approach utilizing the general rate model (GRM), the capabilities of which are explored and optimized using two isotherm models.
View Article and Find Full Text PDF