Publications by authors named "S Betschel"
Angioedema can occur in the absence of urticaria and can be broadly divided into three main categories: mast cell-mediated (e.g., histamine), non-mast-cell-mediated (bradykinin-induced) and idiopathic angioedema.
View Article and Find Full Text PDFBackground: Despite the use of long-term prophylaxis (LTP) for hereditary angioedema (HAE), the risk of having an attack remains and patients with HAE and on LTP may still experience attacks that can be life threatening. However, the behavioralpatterns and perspectives surrounding HAE attack management by patients on LTP are not fully understood.
Objective: This survey aimed to better understand and compare the behavioral patterns and perspectives, including attitudesand perceptions associated with on-demand treatment among patients on LTP versus those using on-demand therapy only.
Real-world outcomes of patients with hereditary angioedema with normal C1-inhibitor function and patients with idiopathic angioedema of unknown etiology in Canada.
Allergy Asthma Clin Immunol
September 2024
Article Synopsis
- The study examines Hereditary angioedema with normal C1-inhibitor function (HAE nC1-INH) and idiopathic angioedema of unknown etiology (AE-UNK) in Canada by analyzing electronic health records from 2012 to 2022.
- Out of 60 patients analyzed, the average age of symptom onset was 21.5 for HAE nC1-INH and 23 for AE-UNK, with significant differences in triggers for episodes and treatment received post-diagnosis.
- The results highlight that while most patients received long-term prophylaxis after diagnosis, the types of treatments and the prevalence of angioedema attacks varied between the two conditions, indicating distinct
Background: Hereditary angioedema (HAE) is characterized by debilitating attacks of tissue swelling in various locations. While guidelines recommend the importance of early on-demand treatment, recent data indicate that many patients delay or do not treat their attacks.
Objective: This survey aimed to investigate patient behavior and evaluate the key factors that drive on-demand treatment decision-making, as reported by those living with HAE.