Publications by authors named "S Besisik"
Article Synopsis
- Graft-versus-host disease (GvHD) is a serious complication after stem cell transplants, and mesenchymal stem cells (MSCs) are being studied as a potential treatment for cases resistant to steroids.
- A study analyzed 36 patients who received umbilical cord-derived MSCs for steroid refractory acute GvHD, finding a median patient age of 39 and a response rate of about 24% after two months.
- The study concluded that MSC therapy could improve response rates in acute GvHD, particularly in younger patients with higher platelet counts, while noting a 33% survival rate at six months post-treatment.
Thrombotic thrombocytopenic purpura (TTP) is one of the rare group disorders classified as thrombotic microangiopathies (TMAs). Approximately 90% of TTP developed immune-mediation by the formation of antibodies against the enzyme ADAMTS-13. The exact cause is unknown.
View Article and Find Full Text PDFBackground: Tumors indicating the advanced stage of mycosis fungoides (MF) have a rich clinical spectrum. Although it is known that the prognosis of MF generally worsens following the development of tumors, some cases may have a relatively indolent course, and the role of clinical characteristics regarding prognosis has still not been well understood.
Methods: MF patients were retrospectively evaluated regarding the development of tumors.
Multiple myeloma (MM) is a haematological malignancy primarily affecting the elderly, with a striking male predilection and ethnic disparities in incidence. Familial predisposition to MM has long been recognized, but the genetic underpinnings remain elusive. This study aimed to investigate germline variants in Turkish families with recurrent MM cases.
View Article and Find Full Text PDFBackground And Aim: Radioembolization (RE) is a one of the palliative treatments that have been used to down stage and/or increase the survival time in intermediate-advanced stages of HCC. We aimed to evaluate the clinical impact of RE and the clinical use of the albumin-bilirubin (ALBI) score as a predictor for survival in HCC patients.
Materials And Methods: Fifty-nine unresectable hepatocellular carcinoma (HCC) patients were enrolled.