Publications by authors named "S Bendiks"

Background: Chronic pain and non-prescribed substance use are associated with lower retention in opioid use disorder (OUD) treatment. We examined the associations of perceived capacity to tolerate uncomfortable physical sensations (discomfort intolerance and discomfort avoidance) and cannabis and alcohol use among persons with chronic pain receiving prescription buprenorphine for OUD.

Methods: This study utilizes baseline data from 163 persons with chronic pain receiving prescription buprenorphine for OUD enrolled in the Treating Opioid use, Persistent Pain, and Sadness (TOPPS) intervention trial.

View Article and Find Full Text PDF
Article Synopsis
  • The TOPPS study is a randomized controlled trial aimed at helping individuals with opioid use disorder who are also dealing with chronic pain and depression, comparing a behavioral intervention to a health education control.* -
  • Participants will be treated with either a phone-based intervention over three months or a control condition to assess changes in pain, depression, and retention in buprenorphine treatment.* -
  • The study seeks to evaluate not only the effectiveness of the TOPPS intervention but also its potential as a widely applicable solution in improving the health outcomes of patients in buprenorphine treatment programs.*
View Article and Find Full Text PDF

Background: To estimate the effects on pain of two medications (low-dose naltrexone and gabapentin) compared to placebo among people with HIV (PWH) with heavy alcohol use and chronic pain.

Methods: We conducted a pilot, randomized, double-blinded, 3-arm study of PWH with chronic pain and past-year heavy alcohol use in 2021. Participants were recruited in St.

View Article and Find Full Text PDF
Article Synopsis
  • A study called the St PETER HIV trial explored how abstaining from alcohol and tobacco affects mental health in people with HIV, involving 400 participants in Russia.
  • The researchers looked at the relationship between 30-day point prevalence abstinence (PPA) from alcohol and/or smoking and symptoms of anxiety and depression over 1, 3, 6, and 12 months using established mental health scales.
  • While initial analyses didn't find strong differences in mental health between groups over time, some patterns in depressive symptoms were noted, suggesting more research is needed, especially with larger sample sizes and longer periods of abstinence.
View Article and Find Full Text PDF

Background: Delayed CD4 recovery after initiating antiretroviral therapy (ART) is a novel potential mechanism by which alcohol consumption leads to increased morbidity and mortality in people with HIV. We hypothesized that alcohol consumption at ART initiation is associated with slower CD4 recovery.

Methods: We retrospectively analyzed 2 pooled longitudinal alcohol/HIV cohorts (2014-2019) in St.

View Article and Find Full Text PDF