Publications by authors named "S Belaiche"
Nirmatrelvir/ritonavir is a promising option for preventing severe COVID-19 in solid organ transplant recipients with SARS-CoV-2 infection. However, concerns have arisen regarding potential drug interactions with calcineurin inhibitors (CNI). This two-phase multicentre retrospective study, involving 113 patients on tacrolimus and 13 on cyclosporine A, aimed to assess the feasibility and outcomes of recommendations issued by The French societies of transplantation (SFT) and pharmacology (SFPT) for CNI management in this context.
View Article and Find Full Text PDFThe characterization of drug-drug interactions (DDIs) may require the use of several different tools, such as the thesaurus issued by our national health agency (i.e., ANSM), the metabolic pathways table from the Geneva University Hospital (GUH), and DDI-Predictor (DDI-P).
View Article and Find Full Text PDFArticle Synopsis
- The study examined medication non-adherence (NA) in French adult and pediatric recipients after allogeneic hematopoietic cell transplantation (allo-HCT), finding about 75% of both groups reported NA.
- Key factors linked to NA in adults included being under 50 years old, using specific medications (cyclosporine, valacyclovir/acyclovir), and experiencing side effects, with age being the most significant factor.
- The research is the first of its kind in France and indicates a need for further studies, particularly to better understand NA in pediatric patients who are most vulnerable.