Publications by authors named "S Bejrachandra"
Article Synopsis
- - A rare Rh variant known as DEL phenotype can lead to anti-D alloimmunization in patients typed as D-negative (D-) who receive DEL red blood cells, highlighting limitations in routine blood typing.
- - A 17-year-old D- Thai male with immunodeficiency developed anti-D antibodies after multiple transfusions, prompting an investigation of the blood donors which revealed that many were actually DEL positive despite standard D- typing.
- - This case underscores the need for enhanced blood management policies in Thailand, advocating for molecular testing to correctly identify DEL phenotypes and prevent alloimmunization in D- patients.
Purpose: Co and Co antigens of the Colton (CO) blood group system are implicated in acute and delayed hemolytic transfusion reactions (HTRs). Owing to the inadequate supply of specific antiserum, data on CO phenotypes remain limited. This study aimed to develop genotyping methods to predict Co and Co antigens and to estimate transfusion-induced alloimmunization risks in three Thai blood donor populations.
View Article and Find Full Text PDFBackground And Objectives: High-frequency antigen En (MNS 28) is expressed on glycophorin A (GPA). En(a-) individuals can form anti-En when exposed to GPA. A Thai patient formed an antibody that reacted against all reagent red blood cells (RBCs).
View Article and Find Full Text PDFBackground: Two antithetical antigens, Doa and Dob of the Dombrock (DO) blood group system are implicated in acute to delayed hemolytic transfusion reactions among patients with anti-Doa or anti-Dob. Given the unavailability of specific antiserum, a polymerase chain reaction with sequence-specific primer (PCR-SSP) was developed to identify DO*A and DO*B alleles. This study aimed to determine DO*A and DO*B allele frequencies and to predict transfusion-induced alloimmunization risks in three Thai blood donor populations.
View Article and Find Full Text PDFObjectives: To determine the genetic background underlying the P phenotype in two Thai sisters suffering from multiple spontaneous abortions.
Background: The P antigen is carried by globoside, an abundant glycosphingolipid in the red blood cell (RBC) membrane. Inactivating mutations in the 3-β-N-acetylgalactosaminyltransferase gene (B3GALNT1) give rise to the rare P phenotype, which lack the P and PX2 antigens.