Publications by authors named "S Baumgarten"
Article Synopsis
- 28 adults participated in a study to examine the effects of ketone ester (KE) supplementation on exercise performance, consuming either low (KE-LO) or high (KE-HI) doses or a placebo before exercise.
- The results showed that KE ingestion significantly increased levels of ß-hydroxybutyrate, a key ketone body, but did not improve exercise economy or efficiency during submaximal cycling compared to the placebo.
- Interestingly, participants had higher heart rate and ventilation with KE intake, but the peak power output was lower in the high dose group (KE-HI) compared to both the low dose and placebo, despite no changes in overall oxygen uptake (V̇O2peak).
Infertility affects 15 % of couples in the US, and many turn to assisted reproductive technologies, including in vitro fertilization and subsequent frozen embryo transfer (FET) to become pregnant. This study aimed to perform a broad assessment of the maternal immune system to determine if there are systemic differences on the day of FET in cycles that result in a live birth compared to those that do not. Women undergoing FET of euploid embryos were recruited and blood was collected on the day of FET as well as at early timepoints in pregnancy.
View Article and Find Full Text PDFApicomplexan and trypanosomatid parasites have evolved a wide range of post-transcriptional processes that allow them to replicate, differentiate, and transmit within and among multiple different tissue, host, and vector environments. In this review, we highlight the recent advances that point toward the regulatory potential of RNA modifications in mediating these processes on the coding and noncoding transcriptome throughout the life cycle of protozoan parasites. We discuss the recent technical advancements enabling the study of the 'epitranscriptome' and how parasites evolved RNA modification-mediated mechanisms adapted to their unique lifestyles.
View Article and Find Full Text PDFEffects of graft detachment on the central corneal thickness after uncomplicated Descemet membrane endothelial keratoplasty.
Graefes Arch Clin Exp Ophthalmol
September 2024
Purpose: To determine if early central corneal thickness (CCT) and best-corrected visual acuity (BCVA) changes indicate graft detachment after uncomplicated Descemet membrane endothelial keratoplasty (DMEK).
Methods: In this analysis of our prospectively collected ADDA registry data ( https://drks.de/search/de/trial/DRKS00027180 ), 45 pseudophakic eyes underwent DMEK surgery at the Department of Ophthalmology, RWTH Aachen University.
Article Synopsis
- The study focuses on using parenteral nutrition (PN) for premature newborns, who are at risk for liver disease associated with PN, and aims to develop predictive models for this condition.
- Researchers utilized liver organoids derived from induced pluripotent stem cells to simulate the liver environment and assess the effects of different lipid treatments used in PN.
- Results indicated that both lipid treatments led to lipid accumulation in liver cells and decreased liver function markers, suggesting that liver organoids could serve as a useful platform for testing new, less harmful PN solutions.