Publications by authors named "S Bartolini"
: Glioblastoma -wildtype (GBM -wt) is the most aggressive brain tumor in adults and is characterized by an immunosuppressive microenvironment. Different factors shaping its tumor microenvironment (TME) regulate tumor progression and treatment response. The aim of this study was to characterize the main immunosuppressive elements of the GBM -wt TME.
View Article and Find Full Text PDFHuman papilloma virus (HPV) infection is responsible for 4.5% of cancers worldwide, i.e.
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- A systematic review and meta-analysis revealed that economic income significantly affects the survival rates of glioblastoma patients, with those having lower income experiencing poorer outcomes.
- The study analyzed 12 research papers, encompassing over 143,000 patients, and found that a lower economic income correlated with a hazard ratio of 1.09, indicating a higher risk of mortality.
- Factors like the type of healthcare system and the timing of treatment had no significant impact on survival, highlighting the need to address socioeconomic disparities in cancer care to improve outcomes for disadvantaged patients.
Seven auxin-producing endophytic bacterial strains ( spp., , spp.), and two different combinations of these strains were used to verify their influence on tomato during germination and development in hydroponic conditions where, as a novelty for Canestrino di Lucca cultivar, endophytic bacteria were inoculated.
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- TP53 mutations are common in patients with IDH-wildtype GBM, but their impact on patient prognosis has not been well studied.
- This study analyzed 97 patients under 70 years old who received specific treatments and found that 19.4% had TP53 mutations, but this did not significantly affect overall survival rates.
- Although TP53 mutations didn't correlate with survival for all patients, they were linked to longer survival in a small group with overall survival over 36 months, indicating they might be important for certain long-term survivors.