Living donor liver transplantation in South Africa: the donor experience.

Background: Living donor liver transplantation (LDLT) plays a crucial role in liver transplant programmes, particularly in regions with a scarcity of deceased donor organs and especially for paediatric recipients. LDLT is a complex and demanding procedure which places a healthy living donor in harm's way. Donor safety is therefore the overriding concern.

Occupations, social vulnerability and HIV/STI risk: The case of bisexual Latino men in the New York City metropolitan area.

This article examines the relationship between the work environment, type of occupation and sexual risk-taking among behaviourally bisexual Latino men, in which data were analysed from a mixed-methods study of 148 behaviourally bisexual Latino men, aged 18-60. The authors draw on both sex market theory and the literature on structural violence and labour to situate sexual risk-taking within broader dimensions of social inequalities and organisation. Manual labour, hospitality and retail/professional fields are examined and compared.

Humidified nasal continuous positive airway pressure in obstructive sleep apnoea.

Heated humidification of nasal continuous positive airway pressure (nCPAP) reduces upper airway symptoms and improves initial use in obstructive sleep apnoea syndrome (OSAS). The present study aimed to assess the effect of heated humidification of nCPAP on upper airway symptoms and initial use in obstructive sleep apnoea. This study was of a randomised, crossover design.

Mandibular advancement splint improves indices of obstructive sleep apnoea and snoring but side effects are common.

Aim: To assess the efficacy of a mandibular advancement splint (MAS) in the treatment of obstructive sleep apnoea syndrome (OSAS).

Methods: Nineteen patients using a MAS for symptomatic OSAS underwent polysomnography, with MAS use randomised to one half of the night. Indices of snoring and OSAS were compared.

Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins.

P-Glycoproteins are transmembrane proteins associated with acquired multidrug resistance in mammalian cells and some protozoan parasites by a process of active drug export. P-glycoproteins contain two nucleotide binding domains which couple ATP to the drug transport process. The region between the nucleotide binding domains of P-glycoproteins, termed the internucleotide binding domain (IBD), was PCR-amplified from adult and larval cDNA libraries using degenerate primers.