Association between dairy products intake and frailty transitions in older adults: The InCHIANTI cohort study.

Objective: To evaluate the association between dairy products consumption and the probability of frailty transitions in community-dwelling older adults.

Design: Longitudinal study.

Setting And Participants: We included 863 community-dwelling participants ≥65 years from the Chianti region in Italy.

Has Muscle Power Better Discriminative Capacity Compared To Muscle Strength In Predicting Worsening Disability In Older Adults?

Background: Poor muscle strength is a risk factor for disability; nonetheless its discriminative capacity in identifying people who will become disabled is poor. We evaluated whether muscle power, which also is a risk factor for disability, has better discriminative capacity compared to muscle strength.

Methods: We used data from the population based InCHIANTI study.

Novel loci and biomedical consequences of iron homoeostasis variation.

Iron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation are unclear. In a meta-analysis of 12 cohorts involving 91,675 participants, we found 43 genomic loci associated with either hepcidin or sTfR concentration, of which 15 previously unreported.

Cardiovascular health, measured using Life's Essential 8, is associated with reduced dementia risk among older men and women.

Background: Dementia poses considerable challenges to healthy aging. Prevention and management of dementia are essential given the lack of effective treatments for this condition.

Methods: A secondary data analysis was conducted using data from 928 InCHIANTI study participants (55% female) aged 65 years and older without dementia at baseline.