Publications by authors named "S Balser"

Article Synopsis
  • The RUSTIC trial evaluated the pharmacokinetic (PK) similarity of the proposed ustekinumab biosimilar FYB202 with the EU-approved and US-licensed versions after a single 45-mg injection to 491 healthy adults.
  • Results showed that all comparisons of PK characteristics were similar, as the concentration measurements fell within the accepted range of 80%-125%.
  • Safety analyses indicated that FYB202 had a lower rate of positive antidrug antibody results compared to reference drugs, supporting its marketing authorization alongside further studies in plaque psoriasis patients.
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With the rapid increase in the aging population, more attention has been paid to studying older adults with dementia. Despite the fact that older adults with dementia are more likely to be abused compared to their cognitively intact counterparts, little attention has been paid to abuse within this population. This systematic review, conducted using the PRISMA model, aims to critically examine, evaluate, and synthesize literature on protective factors and adverse effects of elder abuse by informal caregivers among individuals with dementia.

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Here, we present a covalent nanolayer system that consists of a conductive and biorepulsive base layer topped by a layer carrying biorecognition sites. The layers are built up by electropolymerization of pyrrole derivatives that either carry polyglycerol brushes (for biorepulsivity) or glycoside moieties (as biorecognition sites). The polypyrrole backbone makes the resulting nanolayer systems conductive, opening the opportunity for constructing an electrochemistry-based sensor system.

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Polyglycerol (PG) based surfaces materials and surfaces are well-established bio-compatible materials. Crosslinking of the dendrimeric molecules via their OH groups improves their mechanical stability up to the point that free-standing materials can be attained. Here, we investigate the effect of different crosslinkers on PG films regarding their biorepulsivity and mechanical properties.

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Elder abuse is related to numerous adverse health and mental health conditions in older adults and some studies indicated higher rates of elder abuse in ethnic and racial minority populations than non-Hispanic Whites. This current study aims to summarize the risk and protective factors associated with elder abuse in community-dwelling racial minorities. A systematic review was conducted following Preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines.

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