Short-term effect of removal of fixed orthodontic appliances on gingival health and subgingival microbiota: a prospective cohort study.

Objective: The aim of this prospective longitudinal study was to assess and compare the microbiological and clinical parameters of patients wearing a fixed orthodontic appliance, as opposed to 10 days after the bracket had been removed following treatment.

Materials And Methods: In total, 122 patients participated in this study; 61 of the subjects were assessed at baseline (wearing a fixed orthodontic appliance: T1) and 10 days after bracket removal (T2). The other 61 individuals had never worn an orthodontic appliance before and these subjects served as controls (CT).

Determination of periodontopathogens in patients with Cri du chat syndrome.

Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in a group with Cri du chat syndrome and another without the síndrome, to assess a potential microbiological predisposition to suffer a periodontitis.

Interleukin 1 receptor antagonist (IL1RN) genetic variations condition post-orthodontic external root resorption in endodontically-treated teeth.

External apical root resorption (EARR) is a frequent iatrogenic problem following orthodontic treatment in endodontically-treated teeth, about which the literature reports substantial variability in post-orthodontic treatment EARR responses. The main focus of the present study is to clarify whether variants in the interleukin-1 receptor antagonist gene coding for the IL-1ra protein have a positive/negative influence on EARR of endodontically-treated teeth. Ninety-three orthodontic patients were genetically screened for a single nucleotide polymorphism (SNP:rs419598) in the IL1 cluster.

Postorthodontic external root resorption is associated with IL1 receptor antagonist gene variations.

Objective: External apical root resorption (EARR) is a frequent iatrogenic effect of orthodontic treatment. Patients with genetic variants in the interleukin 1 gene have been related to an increased risk of suffering EARR. The objective of this study is to determine whether variants in the interleukin 1 receptor antagonist gene are positively/negatively associated with interleukin 1 gene polymorphisms, particularly in relation to the clinical features of EARR patients.