Publications by authors named "S Baldacci"
Health status of Italian children living close to cultivations sprayed with pesticides.
Int J Tuberc Lung Dis
October 2024
Article Synopsis
- Traffic-related air and noise pollution significantly impact public health, particularly affecting allergic and respiratory conditions in adults and the elderly population.* -
- A study involving 645 residents in Pisa, Italy, found that many reported exposure to traffic-related pollution, with higher odds of allergic rhinitis linked to vehicular traffic and elevated noise levels, especially in older individuals.* -
- The research underscores the importance of understanding how traffic-related exposure affects the elderly, given the growing aging population worldwide.*
Due to the increasing importance of exposome in environmental epidemiology, feasibility and usefulness of an Environmental Data Management System (EDMS) using Open Data was evaluated. The EDMS includes data from 10 European cities (Celje (Slovenia), Łódź (Poland), Manchester (UK), Palermo (Italy), Paris (France), Porto (Portugal), Regensburg (Germany), Reus (Spain), Rijeka (Croatia), Thessaloniki (Greece)) about external non-specific and specific exposome factors at the city or country level (2017-2020). Findings showed that the highest values of life expectancy were in Reus females (86 years) and Palermo males (81 years).
View Article and Find Full Text PDFObjectives: occupational exposure to vapours, gases, dusts and fumes (VGDF) plays an important role in the development and exacerbation of respiratory diseases. The aim of this study is to evaluate the possible association of occupational exposure to airborne pollutants and chronic respiratory diseases.
Design: multicase-control study.
Article Synopsis
- Activating point mutations in the MET tyrosine kinase domain are identified as oncogenic drivers in various cancers, occurring in about 0.5% of cases, particularly in certain papillary renal cell carcinomas.
- Specific mutations at positions H1094, L1195, F1200, D1228, Y1230, and M1250 were labeled as oncogenic or likely oncogenic based on genetic profiling.
- Preclinical models and patient responses indicate that these mutations may enhance sensitivity to MET inhibitors, highlighting the potential for targeted precision treatments in oncology.