Meta-analysis to determine the effects of supplementation of niacin during the transition or lactating period on performance in dairy cows.

Niacin, a key component of pyridine nucleotides, plays a vital role in over 200 metabolic reactions, including carbohydrate, lipid, and AA metabolism. This meta-analysis aimed to evaluate the effects of niacin supplementation on lactational performance in dairy cows. We hypothesized that niacin supplementation during the transition or lactating periods would enhance the productive performance of dairy cows.

Expression of c-erb-B2 oncoprotein as a neoantigen strategy to repurpose anti-neu antibody therapy in a model of melanoma.

In this study, we tested a novel approach of "repurposing" a biomarker typically associated with breast cancer for use in melanoma. HER2/neu is a well characterized biomarker in breast cancer for which effective anti-HER2/neu therapies are readily available. We constructed a lentivirus encoding c-erb-B2, an animal (rat) homolog to HER2/neu.

The designing of magnetic nanomaterials synthesis and applications in dye degradation: a review.

Numerous activities, including rapid industrialization, population increase, and agricultural practices, have continuously contaminated freshwater resources. One of the main risks to aquatic life and human health is water pollution, which can lead to a number of extremely dangerous illnesses, including cancer, asthma, and gastrointestinal problems. The contaminated wastewater could be cleaned using a variety of traditional and cutting-edge techniques.

Molecular markers of proliferation, DNA repair, and immune infiltration defines high-risk subset of resectable retroperitoneal sarcomas.

Introduction: For retroperitoneal sarcomas (RPS), aggressive surgical resection offers the only chance for a cure; however, 5-year survival remains below 65%. Therefore, there is a critical need to identify drivers of poor clinical outcomes.

Materials And Methods: To identify biomarkers of tumors likely to recur following curative intent resection, we performed genomic and transcriptomic sequencing for 47 and 34 patients, respectively, with non-metastatic RPS at a single, high-volume sarcoma center.

Expression of c-erb-B2 oncoprotein as a neoantigen strategy to repurpose anti-neu antibody therapy in a model of melanoma.

In this study, we tested a novel approach of "repurposing" a biomarker typically associated with breast cancer for use in melanoma. HER2/neu is a well characterized biomarker in breast cancer for which effective anti-HER2/neu therapies are readily available. We constructed a lentivirus encoding c-erb-B2 (the animal homolog to HER2/neu).