Clinical Outcomes Through Two Years for Infants With Bronchopulmonary Dysplasia and Tracheomalacia.

Background: Tracheomalacia (TM) is common in infants with bronchopulmonary dysplasia (BPD) and associated with respiratory morbidity. Assessment of TM was historically via bronchoscopy, but recent studies demonstrate that ultrashort echo-time (UTE) magnetic resonance imaging (MRI) can accurately assess TM in neonates.

Research Question: Do neonates with MRI-identified TM and BPD have increased respiratory morbidity through age 2 years?

Methods: We performed an observational cohort study of 54 subjects with BPD and assessed TM using UTE MRI at term-equivalent age.

Controlling strain localization in thin films with nanoindenter tip sharpness.

Thin film nanoindentation has increased interest due to its usage in various applications. It is virtually impossible to measure thin film elastic modulus without the substrate influence. Several different methods exist to obtain the true thin film's elastic modulus with no attention given to investigate what parameters can improve insight into thin film mechanical property measurement.

Caregiver Experiences with a Trauma-Informed Parenting Program: Examining the Resource Parent Curriculum.

Background: Young people in out-of-home care often have trauma histories that negatively impact their development and well-being. As a result, resource parents often face challenges meeting the needs of these youth, which can be addressed by ensuring access to effective trauma-informed training.

Objective: This qualitative study examined the impacts and helpfulness of a trauma-informed program ( designed for resource parents who care for a young person involved with child welfare.

Longitudinal proteome-wide antibody profiling in Marburg virus survivors identifies wing domain immunogen for vaccine design.

Limited knowledge exists on the quality of polyclonal antibody responses generated following Marburg virus (MARV) infection and its evolution in survivors. In this study, we evaluate MARV proteome-wide antibody repertoire longitudinally in convalescent phase approximately every six months for five years following MARV infection in ten human survivors. Differential kinetics were observed for IgM vs IgG vs IgA epitope diversity, antibody binding, antibody affinity maturation and Fc-receptor interaction to MARV proteins.