Effects of transmural field stimulation in isolated muscle strips from rabbit sphincter of Oddi and duodenum.

The purpose of the study was to compare the effect of transmural field stimulation (TMS) on isolated smooth muscle strips from rabbit sphincter of Oddi (SO), duodenal circular layer (Dc) and duodenal longitudinal layer (D1). The strips were suspended in thermostatically controlled 5-ml organ baths containing Krebs solution constantly bubbled with 5% CO2 in O2. TMS was delivered through platinum electrodes (140 V, 0.

The duodenojejunal junction and Treitz ligament in the regulation of duodenal emptying.

In chronic experiments in dogs the evacuatory and absorptive duodenal functions and the level of duodenogastric reflux (DGR) in sham-operated dogs and dogs with transected Treitz ligament (TL) and resected duodenojejunal junction (DJJ) were studied. The electrophysiologic characteristics of the antrum, duodenum, and DJJ in sham-operated dogs were examined. It was shown that there is a coordination of gastric and duodenal solid carbohydrate food emptying.

[Regulatory role of duodenal evacuation activity in determination of the absorption rate of organic components of duodenal chyme].

The effect of inhibited duodenal motor-evacuation on the rate of protein, glucose, and lipid absorption was studied in chronic experiments in 5 polyfistulous dogs. Evacuation was inhibited by division of Treitz's ligament (a model of duodenostasis). The results of the experiments are evidence of a considerable regulatory effect of chyme evacuation rate on the value of the flow of substances from the enteral medium into the blood.

[The dynamics of the evacuation of carbohydrate and fatty food from the stomach and duodenum].

The dynamics of the duodenal chyme evacuation depended on the absolute quantity of the stomach-evacuated food in dogs. The evacuation of the carbohydrate food was exponential. Fat food was evacuated in equal portions from the stomach and duodenum.