A transfusion recipient lacking a high-incidence antigen (HIA) and has corresponding alloantibody pose a problem in providing compatible blood unit. We encountered a patient with an antibody to an HIA that required identification to assess if compatible blood could be organized. A 65-year-old male was posted for coronary artery bypass grafting surgery.
View Article and Find Full Text PDFThe In antigen of the Indian blood group system is a high-prevalence antigen. The presence of alloanti-In in a recipient may pose a problem in finding compatible blood for transfusion. The aim of this study was to screen blood donors for In and to include individuals found to be In(b-) in our rare donor registry.
View Article and Find Full Text PDFIntroduction: The identification of alloantibodies to high-frequency antigens (HFA) and subsequent transfusion management can be challenging and often poses a problem in finding the compatible blood for transfusion. The aim of this study was to investigate the specificity of the antibody to the HFA causing a hemolytic transfusion reaction (HTR) and procure the compatible blood unit for future transfusion.
Case Presentation: A 4-year-old female met with a head injury that led to intracranial bleeding and surgical intervention was required to remove blood clots.
Background: Discrepancy in "forward/reverse" grouping leads to confusion in assigning ABO group to a person. It could be genetic in nature and classified according to the presence/absent of antigen on red blood cell (RBC) vis-a-vis corresponding alloantibody in plasma.
Aim: The aim of the study was to investigate the grouping anomaly found in a recently delivered woman who required transfusion.
The Indian blood group system (ISBT 023) comprises one lowprevalence antigen, Ina (IN:1), and five high-prevalence antigens: Inb (IN:2), INFI (IN:3), INJA (IN:4), INRA (IN:5), and INSL (IN:6). The antigens are located on the single-pass trans-membrane glycoprotein encoded by the CD44 gene. The present study was designed to identify the prevalence of the INRA- (IN:-5) phenotype and the frequency of its associated allele (IN*02.
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