Publications by authors named "S B SACHS"

The knowledge of Pliensbachian (Early Jurassic, ∼192.9-184.2 Ma) plesiosaurs is notoriously insufficient.

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Alpha-synuclein (aSyn) aggregates in the central nervous system are the main pathological hallmark of Parkinson's disease (PD). ASyn aggregates have also been detected in many peripheral tissues, including the skin, thus providing a novel and accessible target tissue for the detection of PD pathology. Still, a well-established validated quantitative biomarker for early diagnosis of PD that also allows for tracking of disease progression remains lacking.

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Diatoms and bacteria play a vital role in investigating the ecological effects of heavy metals in the environment. Despite separate studies on metal interactions with diatoms and bacteria, there is a significant gap in research regarding heavy metal interactions within a diatom-bacterium system, which closely mirrors natural conditions. In this study, we aim to address this gap by examining the interaction of uranium(VI) (U(VI)) with Achnanthidium saprophilum freshwater diatoms and their natural bacterial community, primarily consisting of four successfully isolated bacterial strains (Acidovorax facilis, Agrobacterium fabrum, Brevundimonas mediterranea, and Pseudomonas peli) from the diatom culture.

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Article Synopsis
  • Autoantibodies against LGI1 are linked to autoimmune encephalitis, impacting the limbic system and causing seizures and memory issues.
  • The study focused on how these autoantibodies influence synaptic structure and function, revealing effects on neurotransmitter release.
  • Results showed that LGI1 autoantibodies enhanced neurotransmission by increasing release probability but did not affect presynaptic calcium channels; however, they reduced certain potassium channel densities.
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