Objectives: The splenial angle (SA), measured on axial DTI colour fractional anisotropy MRI, outperformed the callosal angle (CA) in predicting idiopathic normal pressure hydrocephalus (NPH) patients from those with Alzheimer's dementia, Parkinson's disease (PD) and healthy controls (HC). We investigated its reliability and classification performance on more commonly acquired T1 MPRAGE and FLAIR images.
Methods: SA was measured on axial MPRAGE and FLAIR images in 57 subjects (19 NPH, PD and HC each) by two raters, and compared across groups.
Histoplasmosis, also referred to as Darling's disease, is mainly caused by the thermally dimorphic fungus Histoplasma capsulatum. It is usually contracted by inhaling fungal spores found in soil contaminated with bat or bird droppings, often during activities like cave exploration. Although endemic in certain regions of India, such as the eastern part, and sporadically in southern and northern states, histoplasmosis can manifest with varied clinical presentations, ranging from asymptomatic to severe disseminated disease affecting multiple organs.
View Article and Find Full Text PDFBackground: The use of plaque modification techniques during percutaneous coronary interventions (PCI) has increased. However, these procedures are linked to higher contrast volume and hypotensive episodes, which are risk factors for acute kidney injury (AKI). This study examined the effects of various plaque modification techniques on AKI after PCI.
View Article and Find Full Text PDF