Publications by authors named "S B Melville"
is a Gram-positive anaerobic spore-forming bacterial pathogen of humans and animals. also produces type IV pili (T4P) and has two complete sets of T4P-associated genes, one of which has been shown to produce surface pili needed for cell adherence. One hypothesis about the role of the other set of T4P genes is that they could comprise a system analogous to the type II secretion systems (TTSS) found in Gram-negative bacteria, which is used to export folded proteins from the periplasm through the outer membrane to the extracellular environment.
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- The study aimed to find the best letrozole regimen for inducing ovulation in women with polycystic ovary syndrome (PCOS).
- Conducted at a single fertility clinic between 2015 and 2022, it analyzed 189 ovulation induction cycles among 52 women with PCOS.
- Results showed that higher doses and longer regimens (5 mg for 10 days or similar) significantly improved ovulation rates and reduced time to pregnancy compared to the standard regimen.
Article Synopsis
- The study investigates the rates of unexpected premalignancy and malignancy during hysterectomy for pelvic organ prolapse in a population with limited medical screening access.
- It reviews the medical records of 759 patients at a public hospital from 2007 to 2019, predominantly including Hispanic individuals, with a median age of 57 and a majority being postmenopausal.
- The findings revealed low rates of abnormal pathology, with only 3 cases of endometrial cancer or hyperplasia and 3 cases of cervical cancer, suggesting that rates might be consistent with previous studies despite limited screening.
Article Synopsis
- This study investigated how uterine adenomyosis affects obstetric outcomes in women aged 15-54 during hospital deliveries from 2016 to 2019.
- Using a large dataset, researchers found that women with adenomyosis had higher odds of serious placental complications like placenta previa, accreta, and abruption, and were more likely to have premature deliveries and cesarean sections.
- Overall, the findings indicate that uterine adenomyosis is linked to an increased risk of severe complications for both mothers and infants during childbirth.
Background: In practice, preoperative evaluation prior to hysterectomy varies. Unnecessary preoperative evaluation may add cost and risk with little benefit to the patient.
Objective: This study aimed to describe practice patterns and the associated costs related to preoperative evaluations before hysterectomy for prolapse at a safety-net hospital.