Publications by authors named "S B Levine"

Background: Studies of the association between sex and the risk of incident dementia are inconsistent, in part conceivably due to sex-specific background medical conditions.

Method: A prospective national cohort study which consisted of 112,204 members of a nonprofit Israeli health maintenance organization born between 1902 and 1952 who entered the cohort on January 1, 2002, without a dementia diagnosis and were followed up to January 1, 2020. Participants were aged 50 to 100 years.

View Article and Find Full Text PDF

Background: The levels of biogenesis of lysosome organelles complex 1 subunit 1 (BLOC1S1) control mitochondrial and endolysosome organelle homeostasis and function. Reduced fidelity of these vacuolar organelles is increasingly being recognized as important in instigating cell-autonomous immune cell activation. We reasoned that exploring the role of BLOC1S1 in CD4 T cells may further advance our understanding of regulatory events linked to mitochondrial and/or endolysosomal function in adaptive immunity.

View Article and Find Full Text PDF

Patients receiving palliative care experience stigma associated with their illness, personal identity, and healthcare utilization. These stigmas can occur at any stage of the disease process. Varying stigmas combine to cause palliative care patients to feel misunderstood, contribute to treatment barriers, and further negative stereotypes held by clinicians.

View Article and Find Full Text PDF