Publications by authors named "S B Krumova"
Chronic lymphocytic leukemia (CLL), the most common type of leukemia, remains incurable with conventional therapy. Despite advances in therapies targeting Bruton's tyrosine kinase and anti-apoptotic protein BCL-2, little is known about their effect on red blood cell (RBC) aggregation in blood flow. In this study, we applied a microfluidic device and a newly developed Software Image Flow Analysis to assess the extent of RBC aggregation in CLL patients and to elucidate the hemorheological effects of the commonly applied therapeutics Obinutuzumab/Venetoclax and Ibrutinib.
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- * Overall, 29.7% of students tested positive for infection markers, with Stara Zagora students showing higher rates (33.6%) compared to Sofia students (23%).
- * Higher seropositivity was found in male students (32.8%) compared to females (16.0%), highlighting the need for improved safety protocols and infection control in veterinary training programs.
Article Synopsis
- Monkeypox (mpox) is currently the leading zoonotic disease caused by the orthopoxvirus, with unusual transmission patterns recently observed outside of endemic regions.
- A study was conducted on 181 clinical samples from 42 Bulgarian patients to investigate the presence of monkeypox virus (MPXV) and other orthopoxvirus (OPXV) DNA.
- The results showed MPXV DNA in 23 samples and OPXV DNA in 20 samples, with the highest detection rates in vesicular contents and respiratory secretions, indicating that the virus can persist in various bodily fluids for more than two weeks post-infection.
Nanotechnology is rapidly advancing towards the development of applications for sustainable plant growth and photosynthesis optimization. The nanomaterial/plant interaction has been intensively investigated; however, there is still a gap in knowledge regarding their effect on crop seed development and photosynthetic performance. In the present work, we apply a priming procedure with 10 and 50 mg/L Pluronic-P85-grafted single-walled carbon nanotubes (P85-SWCNT) on garden pea seeds and examine the germination, development, and photosynthetic activity of young seedlings grown on soil substrate.
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- - During summer 2023, Europe saw a small uptick in mpox cases after a major outbreak in 2022, marked by peaks happening at different times in various countries!* - The demographic makeup of the new cases was similar to those from previous reports, maintaining the same trends.
- - All collected case sequences from this recent resurgence belonged to clade IIb, highlighting the need for ongoing control efforts to eliminate mpox in the region.