Publications by authors named "S B Krintel"

Article Synopsis
  • The study aimed to evaluate the effectiveness and safety of abatacept and tofacitinib in treating sarcoidosis patients who were unresponsive to previous treatments.
  • A total of 41 patients were treated with abatacept, while 12 received tofacitinib, with most tofacitinib patients having prior abatacept treatment.
  • After 6 months, both treatments showed high drug survival rates (90% for abatacept, 89% for tofacitinib) and significant responder rates (71% and 67% respectively), indicating they are safe and effective options for patients with persistent symptoms.
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Article Synopsis
  • * The study analyzed data from Danish nationwide registries, including over 14,000 sarcoidosis patients, and revealed an increased hazard ratio for VTE shortly after diagnosis and even after a year.
  • * Overall mortality rates for patients experiencing VTE did not significantly differ between those with sarcoidosis and those without, suggesting that the presence of sarcoidosis increases VTE risk but not necessarily mortality from it.
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Objectives: The aim of the study was to evaluate the treatment response to Interleukin-6-receptor inhibitition (IL-6Ri), primarily tocilizumab, in patients with VEXAS.

Methods: Data were obtained from review of hospital based clinical records and included symptoms, laboratory data, transfusion history, pathology reports, imaging, and treatment.

Results: Fifteen patients were treated with tocilizumab intravenously.

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: To evaluate the influence of low socioeconomic status (SES) on mortality among patients with granulomatosis with polyangiitis (GPA).: Using nationwide registers, we established a cohort of 827 patients diagnosed with GPA in the public hospital system of Denmark. For each patient, information regarding educational level, civil status, employment status, and comorbidities at time of GPA diagnosis was collected.

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