Publications by authors named "S B Hannush"

Article Synopsis
  • - Deep anterior lamellar keratoplasty (DALK) is a surgical technique for treating corneal disorders without affecting the endothelium, which helps prevent rejection and late graft failure compared to traditional penetrating keratoplasty (PK).
  • - The introduction of the big-bubble technique (BBT) improved the efficiency and consistency of DALK by using air to separate corneal layers, resulting in high-quality grafts comparable to PK.
  • - Understanding the anatomy behind BB formation, including the significance of Dua's layer, is essential for successful DALK procedures; ongoing improvements in BBT are increasing its use in corneal transplants with healthy endothelium.
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Purpose Of Review: The Boston Keratoprosthesis Type 1 was pioneered by Claes Dohlman several decades ago. Since its inception, the device has undergone multiple revisions to address challenges associated with retroprosthetic membrane formation, retention, extrusion, stromal melt and endophthalmitis. Although visual outcomes and retention rates have improved, challenges, especially glaucoma, remain.

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Importance: Determining factors associated with endothelial cell loss after Descemet stripping automated endothelial keratoplasty (DSAEK) could improve long-term graft survival.

Objective: To evaluate the associations of donor, recipient, and operative factors with endothelial cell density (ECD) 3 years after DSAEK in the Cornea Preservation Time Study.

Design, Setting, And Participants: This cohort study was a secondary analysis of data collected in a multicenter, double-masked, randomized clinical trial.

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Purpose: To review the graft survival rate, visual outcomes, and patient demographics of primary penetrating keratoplasty performed at Tenwek Hospital, a mission hospital in rural Kenya.

Methods: A retrospective review was performed of the clinical records of patients who underwent primary penetrating keratoplasty for optical purposes from January 2012 to October 2014. The graft survival rates were constructed using the Kaplan-Meier method, and the effect of clinical and socioeconomic characteristics on time to graft failure were examined using Cox regression models.

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