Publications by authors named "S B Guenther"
Electroencephalography in emerging viral infections: Lessons learned from implementing an EEG unit in a Lassa fever isolation ward in Nigeria.
PLoS Negl Trop Dis
October 2024
Article Synopsis
- EEG is a special test used to check how the brain works, especially in diagnosing conditions like epilepsy.
- Lassa fever and other viral infections can cause brain issues, but it's not always clear if they are caused directly by the virus or other problems in the body.
- Setting up an EEG unit in a hospital for Lassa fever is hard because of issues like power outages, heat, and needing special safety gear, but doctors can still learn a lot from it to help treat patients.
Background: Gemcitabine plus cisplatin (GC) is a highly active and commonly used regimen in locally advanced/metastatic urothelial carcinoma (la/mUC). With GC, cisplatin is dosed at 70 mg/m on day 1 of a 3-week cycle; however, for many patients, impaired renal or cardiac function, neuropathy, or poor performance status (PS) can preclude the use of cisplatin. A promising alternative is split-dose GC, in which the cisplatin dose is divided over 2 days.
View Article and Find Full Text PDFThe contribution of endocardial cells (EdCs) to the hematopoietic lineages has been strongly debated. Here, we provide evidence that in zebrafish, the endocardium gives rise to and maintains a stable population of hematopoietic cells. Using single-cell sequencing, we identify an endocardial subpopulation expressing enriched levels of hematopoietic-promoting genes.
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- Scientists wanted to see if a new method called hypothermic oxygenated machine perfusion (HOPE) is better for keeping donor hearts alive before they are transplanted, compared to the traditional cold storage method.
- They did a big study with 229 patients across 15 transplant centers in Europe to compare these two methods.
- The main goal was to find out if using HOPE reduces serious problems after heart transplant surgery, like heart failure or rejection, within the first 30 days.
Recent advances in visual decoding have enabled the classification and reconstruction of perceived images from the brain. However, previous approaches have predominantly relied on stationary, costly equipment like fMRI or high-density EEG, limiting the real-world availability and applicability of such projects. Additionally, several EEG-based paradigms have utilized artifactual, rather than stimulus-related information yielding flawed classification and reconstruction results.
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