Extracellular Matrix Protein 1 Gene Mutation in Turkish Patients with Lipoid Proteinosis.

Background: Lipoid proteinosis (LP) is a rare autosomal recessive genodermatosis characterized by mucocutaneous lesions and hoarseness of voice that develop in early childhood. LP is caused by mutation in the extracellular matrix protein 1 () gene, which is located on 1q21.2.

Serum ghrelin levels in patients with Behcet's disease.

Introduction: Behcet's disease (BD) is a chronic, relapsing, systemic vasculitis of unknown etiology.

Aim: To measure serum ghrelin levels in BD patients and healthy controls and to investigate its association with metabolic syndrome (MetS).

Material And Methods: Thirty BD patients and 30 healthy individuals were enrolled in the study.

Prevalence of glaucoma in patients with vitiligo.

Vitiligo is an acquired idiopathic disease characterized by depigmented maculae and melanocytic destruction. We determined the prevalence of glaucoma in 49 patients who had presented to the dermatology polyclinic with vitiligo and compared that with the prevalence of glaucoma in 20 age- and sex-matched healthy controls. All patients were given an ophthalmologic examination to identify any glaucomatous changes.

Ghrelin in the pilosebaceous unit: alteration of ghrelin in patients with acne vulgaris.

Background: Ghrelin in the pilosebaceous tissues of human skin and ghrelin levels in patients with acne vulgaris have not yet been investigated.

Objective: The purpose of this study was to screen ghrelin immunoreactivity by immunohistochemistry in human pilosebaceous tissues of human skin and also to determine the quantities of ghrelin in the serum of the patients with acne vulgaris.

Methods: 30 patients presenting with acne vulgaris and 30 control subjects participated in this study.