Hyperglycemia during intravenous fluid therapy. A clue to the presence of diabetes mellitus.

Twenty-two patients receiving 5 per cent glucose solution intravenously during an acute illness were studied for evidence of hyperglycemia. Those in whom blood sugar rose above 100 mg per 100 ml (Folin-Wu) during intravenous therapy subsequently had impairment of carbohydrate tolerance as measured by oral glucose tolerance tests. The data collected suggested that blood sugar of 100 mg per 100 ml (Folin-Wu) or more developing in such a setting is a clue to the presence of diabetes mellitus.

DIABETES INSIPIDUS. TREATMENT WITH 8-LYSINE VASOPRESSIN IN A NASAL SPRAY.

Synthetic 8-lysine vasopressin administered as a nasal spray to three patients with diabetes insipidus resulted in excellent control in one. In the other two it was of some value as therapy supplemental to pitressin tannate in oil. The patient who was adequately controlled with "spray therapy" alone required the sprays every three hours during the day, but none during the night.