Disorder-Induced Anomalous Mobility Enhancement in Confined Geometries.

Strong, scale-free disorder disrupts typical transport properties like the Stokes-Einstein relation and linear response, leading to anomalous diffusion observed in amorphous materials, glasses, living cells, and other systems. Our study reveals that the combination of scale-free quenched disorder and geometrical constraints induces unconventional single-particle mobility behavior. Specifically, in a two-dimensional channel with width w, under external drive, tighter geometrical constraints (smaller w) enhance mobility.

Universal to nonuniversal transition of the statistics of rare events during the spread of random walks.

Through numerous experiments that analyzed rare event statistics in heterogeneous media, it was discovered that in many cases the probability density function for particle position, P(X,t), exhibits a slower decay rate than the Gaussian function. Typically, the decay behavior is exponential, referred to as Laplace tails. However, many systems exhibit an even slower decay rate, such as power-law, log-normal, or stretched exponential.

Triggering Gaussian-to-Exponential Transition of Displacement Distribution in Polymer Nanocomposites Adsorption-Induced Trapping.

In many disordered systems, the diffusion of classical particles is described by a displacement distribution (, ) that displays exponential tails instead of Gaussian statistics expected for Brownian motion. However, the experimental demonstration of control of this behavior by increasing the disorder strength has remained challenging. In this work, we explore the Gaussian-to-exponential transition by using diffusion of poly(ethylene glycol) (PEG) in attractive nanoparticle-polymer mixtures and controlling the volume fraction of the nanoparticles.

Doxorubicin-Loaded Polyelectrolyte Multilayer Capsules Modified with Antitumor DR5-Specific TRAIL Variant for Targeted Drug Delivery to Tumor Cells.

Recently, biodegradable polyelectrolyte multilayer capsules (PMC) have been proposed for anticancer drug delivery. In many cases, microencapsulation allows to concentrate the substance locally and prolong its flow to the cells. To reduce systemic toxicity when delivering highly toxic drugs, such as doxorubicin (DOX), the development of a combined delivery system is of paramount importance.

Self-assembly of two-dimensional, amorphous materials on a liquid substrate.

Recent experimental utilization of liquid substrate in the production of two-dimensional crystals, such as graphene, together with a general interest in amorphous materials, raises the following question: is it beneficial to use a liquid substrate to optimize amorphous material production? Inspired by epitaxial growth, we use a two-dimensional coarse-grained model of interacting particles to show that introducing a motion for the substrate atoms improves the self-assembly process of particles that move on top of the substrate. We find that a specific amount of substrate liquidity (for a given sample temperature) is needed to achieve optimal self-assembly. Our results illustrate the opportunities that the combination of different degrees of freedom provides to the self-assembly processes.