Evaluating seagrass lipid biomarkers as indicator for organic carbon provenance and storage capacity in Zostera marina (L.) sediments.

Seagrass meadows are vital blue carbon habitats, with sedimentary organic carbon (OC) originating from both the seagrass itself and external sources. In this study, lipid biomarkers (n-alkanes), a well-known proxy for tracing OC sources, were used to indicate seagrass presence in sediment records and to correlate with sedimentary OC in cold-temperate seagrass (Zostera marina) sediments. We calculated a Zostera-ratio (seagrass/algae and terrestrial plants-ratio) using identified seagrass biomass n-alkanes (C, C, C, C, C) as a fingerprint for seagrass-derived OC.

Osteocalcin in Infancy and Early Childhood and Its Correlation With Later Growth and Body Composition: A Longitudinal Birth Cohort Study.

Background: Osteocalcin is a metabolic active hormone, which correlates positively with bone formation and inversely with body mass index and waist circumference in adults.

Objectives: To investigate whether osteocalcin in infancy and early childhood were related to childhood growth or body composition.

Methods: A Swedish longitudinal birth cohort with blood samples from 551 children from birth until 5 years of age.

High leptin levels in blood are associated with chronic widespread pain in rheumatoid arthritis.

Background: High body mass index (BMI) has been shown to have an association with chronic widespread pain (CWP), both in Rheumatoid arthritis (RA) and in other pain conditions such as fibromyalgia. Research on the adipose tissue and it's adipokines, for example the well described leptin, is emerging. The objective of this study was to determine if there is an association between leptin levels in blood and CWP in patients with RA.

A tool for CRISPR-Cas9 sgRNA evaluation based on computational models of gene expression.

Background: CRISPR is widely used to silence genes by inducing mutations expected to nullify their expression. While numerous computational tools have been developed to design single-guide RNAs (sgRNAs) with high cutting efficiency and minimal off-target effects, only a few tools focus specifically on predicting gene knockouts following CRISPR. These tools consider factors like conservation, amino acid composition, and frameshift likelihood.

Frequent Pain is Common Among 10-11-Year-Old Children with Symptoms of Attention Deficit Hyperactivity Disorder.

Purpose: Adults with neurodevelopmental disorders have an increased risk for chronic pain. This study aimed to describe the prevalence of frequent and multisite pain among children with symptoms of attention deficit hyperactivity disorder (ADHD) and explore potential sex differences in pain prevalence.

Participants And Methods: Children born in 2008 included in the "Halland Health and Growth Study" were invited to a follow-up (n = 1186) in 2018-19.