Publications by authors named "S B Andersson"
Arthritis significantly reduces health-related quality of life, causing pain, fatigue, and decreased physical activity. To address this, exercise is highly recommended. However, men are less likely to participate in rehabilitation compared to women.
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- Neuroblastoma has two main cell types: therapy-sensitive adrenergic (ADRN) and therapy-resistant mesenchymal (MES).
- Researchers used experiments and mathematical models to study how these cell types respond to treatment and whether they are distinct or dynamic states.
- The findings suggest that ADRN and MES are distinct cell types, and their different growth and survival rates, rather than switching between states, significantly influence how the cancer responds to therapy.
Fitusiran is an investigational small interfering RNA therapeutic that targets antithrombin (AT) to rebalance hemostasis in people with hemophilia. Here we present the results of the completed Phase 2 open-label extension study, which evaluated the long-term safety and efficacy of fitusiran in participants with moderate or severe hemophilia A or B, with or without inhibitors. Male participants who had completed the Phase 1 study (NCT02035605) were enrolled.
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- Cognitive impairment (CI) is a common challenge for cancer survivors, and this study investigates the use of digital Goal Management Training (GMT) compared to computerized cognitive training (CCT) to address this issue in cervical cancer survivors (CCS).
- The study involved 35 CCS, who were randomly assigned to either digital GMT or CCT, with both groups showing a high completion rate of 88% and reporting strong satisfaction with the interventions.
- Results indicated that both training methods led to improvements in attention, memory, and self-reported cognitive functioning, suggesting that digital GMT is a feasible option for enhancing cognitive health in cancer survivors while being low-cost and easy to implement.
Purpose: To explore the characteristic quality of health profiles of children with paediatric acquired brain injury (pABI), and to investigate whether improvement in executive function (EF) following cognitive rehabilitation is associated with improvement in health-related quality of life (HRQOL).
Method: A study of secondary endpoints in a blinded, parallel-randomised controlled trial with children (ages 10-17 years) with pABI and executive dysfunction. Data was obtained from 73 children-parent dyads.