Publications by authors named "S Avraham"
Cryopreserved sperm among patients with Oligoasthenoteratozoospermia.
Eur J Obstet Gynecol Reprod Biol
December 2024
Objectives: This study investigates sperm utilization and disposal patterns in Oligoasthenoteratozoospermia (OAT) patients undergoing long-term sperm storage. OAT is a major contributor to male infertility. Cryopreservation is a common practice as a "fertility insurance" in case of further deterioration until azoospermia.
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- Macrophages are diverse cells that inhabit all body tissues, with specific types residing in organs and additional subtypes recruited during injury.
- A specific population of recruited macrophages, marked by certain gene expressions, has been linked to fibrosis in various injury and cancer models.
- Blocking Notch2 increases these macrophages in the lungs, but evidence suggests they actually help reduce fibrosis rather than cause it, highlighting their potential protective role during lung injuries.
Non-used cryopreserved sperm among oncological patients: extra-long-term follow-up and analysis.
J Assist Reprod Genet
December 2024
Article Synopsis
- The study aimed to understand factors affecting the long-term use and disposal of cryopreserved semen straws among cancer patients over nearly three decades.
- Out of 445 participants, 55 used thawed semen for fertility treatments, 65 disposed of their straws, while a majority of 325 did neither, with younger patients showing lower rates of usage and disposal.
- The findings suggest a need for policies on cryopreservation that consider efficiency, cost, and patient demographics, potentially requiring consent from patients before preservation to alleviate unnecessary burdens.
Although many Fertility Centers have adopted day 5 or 6 embryo transfer policy, yet, 30% of embryo transfers in the US are performed on day 3. This is mainly due to concerns related to longer embryo culture effect and higher rates of embryo transfer cancellation on day 5, with no effect on cumulative pregnancy rate. We conducted a retrospective cohort study comparing individual embryo transfer order rank, best embryo for fresh transfer and intention to freeze, of day-3 and day-5 embryos based on their morphology score.
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