Publications by authors named "S Ashina"
Background: Stigma is emerging as an important social contributor to migraine-related disability and other outcomes. Currently, there are no published validated measures of migraine-specific measures of stigma.
Objectives: This secondary post hoc analysis of a cross-sectional cohort study aimed to develop a questionnaire to evaluate migraine-related stigma.
Objective: To systematically examine the literature on the clinical consequences of inadvertent delays in scheduled onabotulinumtoxin A (OTA) therapy for chronic migraine during the COVID-19 pandemic and assess recommendations when access to OTA is limited.
Background: The coronavirus (COVID-19) pandemic was unprecedented in its impact on the global medical community. Most healthcare institutions in the United States (US) and the world had begun significantly limiting elective procedures, undermining management of many debilitating chronic conditions.
Article Synopsis
- The study focuses on the use of botulinum toxin, particularly onabotulinum toxin A (OTA), for treating migraine and post-traumatic headache (PTH) in military personnel and veterans.
- The unique challenges faced by this population, including increased pain intensity and longer headache durations due to combat-related trauma, highlight the need for effective headache management strategies.
- The literature review identified 8 relevant studies, mainly from the U.S., indicating that chronic migraine is the most common diagnosis treated with botulinum toxin, suggesting its effectiveness for preventing such conditions in service members.
Article Synopsis
- * EVs and exosomes, tiny structures released by cells, show promise in treating conditions like osteoarthritis and intervertebral disc disease by reducing inflammation and promoting tissue repair in animal models.
- * While clinical use of EVs and exosomes for chronic pain management is still developing, ongoing research and clinical trials suggest they have substantial potential for future therapies.
Article Synopsis
- Cluster headache (CH) is a severe headache disorder more common in men, typically starting around age 30, and is often misdiagnosed as migraine, particularly in children.
- The condition involves intense pain and various symptoms that can greatly affect patients' quality of life and mental health, with genetic and lifestyle factors potentially contributing to its development.
- Treatment options range from nonpharmacological approaches like lifestyle changes to medications for acute relief and prevention, but many current therapies are only partially effective, prompting ongoing research into new treatments, including emerging interventional procedures and the possible use of psychedelics.