Publications by authors named "S Appu"
Virchows Arch
September 2024
Article Synopsis
- Localized cystic disease of the kidney (LCDK) is a rare, non-progressive condition that can be mistaken for cancer, potentially leading to unnecessary surgeries.
- In a study of 14 patients (ages 3-79, mostly middle-aged), most cases presented as unilateral and many patients experienced flank pain or had incidental findings.
- The lesions were multilocular and benign, lacking malignant features, and a review of 75 other cases supports the idea that LCDK should be included in the differential diagnosis for cystic kidney lesions.
Article Synopsis
- Carcinomas of the seminal vesicle are rare, and this study examined five unique cases using advanced DNA sequencing to better understand their characteristics.
- The tumors included various types, such as an adenocarcinoma post-radiation therapy, a Müllerian-type clear cell carcinoma, and two low-grade mucinous tumors similar to appendiceal tumors, with specific genomic mutations identified.
- Findings indicate that low-grade mucinous neoplasms of the seminal vesicle may behave similarly to their appendiceal counterparts, while other tumors displayed genomic features akin to similar cancers found in different locations, suggesting management strategies could be aligned with those cancers.
