Factors influencing medication adherence among patients with idiopathic inflammatory bowel disease in Greece and Cyprus: a cross-sectional study.

Objective: . Aim: To examine the level of medication adherence among individuals diagnosed with inflammatory bowel disease (IBD) in Greece and Cyprus and assess the demographic, clinical, and psychosocial variables affecting it.

Patients And Methods: Materials and Methods: An anonymous self-administered questionnaire was administered to adult patients attending hospitals and treatment centers in Greece and Cyprus.

Getting our ducks in a row: The need for data utility comparisons of healthcare systems data for clinical trials.

Background: Better use of healthcare systems data, collected as part of interactions between patients and the healthcare system, could transform planning and conduct of randomised controlled trials. Multiple challenges to widespread use include whether healthcare systems data captures sufficiently well the data traditionally captured on case report forms. "Data Utility Comparison Studies" (DUCkS) assess the utility of healthcare systems data for RCTs by comparison to data collected by the trial.

Plasma cell-free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case-control study and an ovarian cancer screening trial.

Analysis of cell-free DNA methylation (cfDNAme), alone or combined with CA125, could help to detect ovarian cancers earlier and may reduce mortality. We assessed cfDNAme in regions of ZNF154, C2CD4D and WNT6 via targeted bisulfite sequencing in diagnostic and early detection (preceding diagnosis) settings. Diagnostic samples were obtained via prospective blood collection in cell-free DNA tubes in a convenience series of patients with a pelvic mass.