Publications by authors named "S Antwi"
Background: Eosinophilic esophagitis (EoE) is an increasingly common cause of food impaction.
Aims: This study aims to provide a nationwide analysis of food impaction in patients with or without EoE diagnosis, concentrating on patient demographics, interventions, outcomes, and development of predictive machine-learning models.
Methods: A retrospective assessment was conducted using Nationwide Emergency Department Sample data from January 1, 2018, to December 31, 2019.
Traditional medicine is widely used in sub-Saharan Africa, particularly in Ghana, where it is commonly integrated with modern orthodox medicine. This study examines the barriers that delay the pursuit of orthodox medical care for prostate cancer (PCa) in Ghana's Central region, where a blend of traditional and modern orthodox medicine exists. The preference for indigenous traditional medicine often results in late-stage presentations of PCa, adversely affecting patient outcomes.
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- Metabolic liver disease is increasingly linked to hepatocellular carcinoma (HCC), but the molecular mechanisms remain poorly understood; this study focuses on DNA methylation's role in HCC associated with metabolic issues.
- The research involved 272 HCC patients and 316 control subjects, revealing 55 DNA methylation markers that effectively distinguished HCC cases from controls, achieving an AUC of 0.79 for accuracy.
- Combining these markers with demographic data improved sensitivity and specificity for identifying patients at risk for metabolic HCC.
Background: Black/African Americans experience a disproportionate cancer burden and mortality rates. Racial/ethnic variation in cancer burden reflects systemic and healthcare inequities, cancer risk factors, and heredity and genomic diversity. Multiple systemic, socio-cultural, economic, and individual factors also contribute to disproportionately low Black/African American participation in cancer clinical trials.
View Article and Find Full Text PDFBackground: Apolipoprotein L1 gene () variants are risk factors for chronic kidney disease (CKD) among Black Americans. Data are sparse on the genetic epidemiology of CKD and the clinical association of variants with CKD in West Africans, a major group in the Black population.
Methods: We conducted a case-control study involving participants from Ghana and Nigeria who had CKD stages 2 through 5, biopsy-proven glomerular disease, or no kidney disease.