Genetic inbreeding load and its individual prediction for milk yield in French dairy sheep.

Background: The magnitude of inbreeding depression depends on the recessive burden of the individual, which can be traced back to the hidden (recessive) inbreeding load among ancestors. However, these ancestors carry different alleles at potentially deleterious loci and therefore there is individual variability of this inbreeding load. Estimation of the additive genetic value for inbreeding load is possible using a decomposition of inbreeding in partial inbreeding components due to ancestors.

Partitioning of the genetic trends of French dairy sheep in Mendelian samplings and long-term contributions.

The genetic trend of milk yield for 4 French dairy sheep breeds (Lacaune, Basco-Béarnaise, Manech Tête Noire, and Manech Tête Rousse) was partitioned in Mendelian sampling trends by categories of animals defined by sex and by selection pathways. Five categories were defined, as follows: (1) artificial insemination (AI) males (after progeny testing), (2) males discarded after progeny testing, (3) natural mating males, (4) dams of males, and (5) dams of females. Dams of males and AI males were the most important sources of genetic progress, as observed in the decomposition in Mendelian sampling trends.

Analysis of Patient Handoff Between Providers at a Tertiary Urban Medical Center.

Introduction: Few studies have quantified the total number of attending and consulting physicians involved in inpatients' care, and no other research quantifies the total number of all providers participating in inpatients' care. The purpose of this study was to calculate the number of attending hand-offs, the attending encounter time, and the total number of providers participating in inpatients' care for all admitted patients at a tertiary urban medical center.

Methods: The study design was an observational retrospective cohort.

Genomic and pedigree estimation of inbreeding depression for semen traits in the Basco-Béarnaise dairy sheep breed.

Inbreeding depression is associated with a decrease in performance and fitness of the animals. The goal of this study was to evaluate pedigree-based and genomic methods to estimate the level of inbreeding and inbreeding depression for 3 semen traits (volume, concentration, and motility score) in the Basco-Béarnaise sheep breed. Data comprised 16,196 (or 15,071) phenotypic records from 620 rams (of which 533 rams had genotypes of 36,464 SNPs).

The scabicide effect of moxidectin in vitro and in experimental animals: Parasitological, histopathological and immunological evaluation.

Scabies is considered one of the commonest dermatological diseases that has a global health burden. Current treatment with ivermectin (IVM) is insufficient and potential drug resistance was noticed. Moxidectin (MOX), with a better pharmacological profile may be a promising alternative.