Assessment of Ploidy Status in Oral Potentially Malignant Disorders - A Systematic Review.

Malignant and potentially malignant epithelial lesions are often associated with various abnormalities such as epithelial dysplasia, abnormal DNA content, loss of heterozygosity, and chromosomal number aberrations. Screening and early detection of such abnormalities facilitates proper care and also helps to prevent further progression of potentially malignant lesions to malignancy. In such way, the presence of DNA aneuploidy in oral potentially malignant disorders (OPMDs) may serve as an indicator for the malignant transforming potential.

A retrospective diagnostic study of prevalence of orofacial calcifications using panoramic radiograph: To insinuate the unseen.

Background: The prevalence of calcifications in the head and neck region has long been observed and has a strong value of presaging systemic illness. The observations of such calcifications in routine panoramic radiographs (PR) demands keen follow-up and health check-up of patients. In developing countries, the use of routine panoramic radiographs is a common one owing to its cost effectiveness and feasibility.

p-TSA.HO mediated one-pot, multi-component synthesis of isatin derived imidazoles as dual-purpose drugs against inflammation and cancer.

A novel one-pot multicomponent reaction was performed to synthesize different imidazole and benzotriazole (BTA) isatin-based medicinally important compounds using (p-TSA·HO) as an economical and operative acid catalyst. The yield of the products was found to be up to a maximum of 92% when using this catalyst. Antioxidant, anti-breast cancer and anti-inflammatory activities of these 13 isatin-based derivatives (named as 5a-m) were assessed.

The influence of carbon concentration on the electronic structure and magnetic properties of carbon implanted ZnO thin films.

The influence of carbon concentration on the electronic and magnetic properties of C-implanted ZnO thin films has been studied using synchrotron radiation based X-ray absorption spectroscopic techniques and vibrating sample magnetometer measurements. 20 keV carbon ions were implanted in ZnO films with different fluences (2 × 10, 4 × 10 and 6 × 10 ions per cm). The pristine ZnO film shows diamagnetic behaviour while the C-implanted films exhibit room temperature ferromagnetism.